Kirk D. Wyatt, MD, MAS

Pediatric Hematologist/Oncologist · Clinical Informatician · Author

About Kirk

Kirk D. Wyatt, MD, MAS is a Pediatric Hematologist/Oncologist and Clinical Informatician practicing in Fargo, North Dakota at Sanford Health. He is board-certified in Pediatrics, Pediatric Hematology/Oncology, and Clinical Informatics.

Kirk serves as Senior Clinical Advisor for Data for the Common Good at the University of Chicago, where he provides translational subject matter expertise to the technical and data standards teams and collaborates with disease-based consortia to facilitate international pediatric oncology data sharing. The Pediatric Cancer Data Commons is the largest publicly-accessible harmonized pediatric oncology clinical dataset, including data on over 45,000 patients with cancer.

His research spans clinical informatics, pediatric oncology data standards, AI in healthcare, and rare disease data aggregation. He is actively involved in developing methods to empower patients to contribute their medical record data for research.

His 2020 Apple Watch research examined the clinical evaluation of patients presenting after abnormal pulse alerts and found that only about 11% received a clinically actionable cardiac diagnosis, raising important questions about unintended consequences of direct-to-consumer health monitoring. This impactful study was ranked in the top 1% of all research outputs by Altmetric and held the fourth-highest Altmetric score among all articles published in JAMIA. It was covered by The Verge, USA Today, Politico, CNET, Fast Company, Becker's Hospital Review, Detroit Free Press, MobiHealthNews, The Telegraph, and the Daily Mail, and was featured on the Wall Street Journal's flagship podcast The Journal. The New England Journal of Medicine published a related letter written by Kirk on smartwatch atrial fibrillation detection.

Kirk trained in pediatrics and pediatric hematology/oncology at Mayo Clinic and holds a Doctor of Medicine from Mayo Clinic Alix School of Medicine and a Master in Advanced Study in Health Informatics from Arizona State University. He earned his Bachelor of Arts in Chemistry from Grand Valley State University.

He is the author of AI Curbside: The Practical Guide for Busy Clinicians, a field guide for physicians looking to integrate AI into their daily workflows safely and effectively.

Credentials & Training

Current Positions

Pediatric Hematologist/Oncologist — Sanford Health (Fargo, ND)
Senior Clinical Advisor — Data for the Common Good

Board Certifications

Pediatrics  ·  Pediatric Hematology/Oncology  ·  Clinical Informatics

Training

Pediatrics Residency — Mayo Clinic
Pediatric Hem/Onc Fellowship — Mayo Clinic

Education

MD — Mayo Clinic Alix School of Medicine
MAS in Health Informatics — Arizona State University
BA Chemistry — Grand Valley State University

Research Focus

Pediatric Cancer Data

Building the largest publicly-available harmonized pediatric oncology dataset with 45,000+ patients.

AI in Healthcare

Application in practice, trials matching, natural language processing, and responsible AI implementation.

Rare Disease Data

Expanding data commons into rare diseases including monogenic epilepsies.

Patient-Contributed Data

Empowering patients to share their data for research.

Natural Language Processing

Using AI to extract health history and treatment information for research.

Recent Publications

Loaded live from PubMed. Showing peer-reviewed articles where Kirk is a listed author.